E-viri
Recenzirano
Odprti dostop
-
Wan, Derrick C; Morgan, Stefanie L; Spencley, Andrew L; Mariano, Natasha; Chang, Erin Y; Shankar, Gautam; Luo, Yunhai; Li, Ted H; Huh, Dana; Huynh, Star K; Garcia, Jasmine M; Dovey, Cole M; Lumb, Jennifer; Liu, Ling; Brown, Katharine V; Bermudez, Abel; Luong, Richard; Zeng, Hong; Mascetti, Victoria L; Pitteri, Sharon J; Wang, Jordon; Tu, Hua; Quarta, Marco; Sebastiano, Vittorio; Nusse, Roel; Rando, Thomas A; Carette, Jan E; Bazan, J Fernando; Wang, Kevin C
Nature communications, 12/2018, Letnik: 9, Številka: 1Journal Article
Royal jelly is the queen-maker for the honey bee Apis mellifera, and has cross-species effects on longevity, fertility, and regeneration in mammals. Despite this knowledge, how royal jelly or its components exert their myriad effects has remained poorly understood. Using mouse embryonic stem cells as a platform, here we report that through its major protein component Royalactin, royal jelly can maintain pluripotency by activating a ground-state pluripotency-like gene network. We further identify Regina, a mammalian structural analog of Royalactin that also induces a naive-like state in mouse embryonic stem cells. This reveals an important innate program for stem cell self-renewal with broad implications in understanding the molecular regulation of stem cell fate across species.
Avtor
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.