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Richardson, Paul G., MD; Smith, Angela R., MD, MS; Triplett, Brandon M., MD; Kernan, Nancy A., MD; Grupp, Stephan A., MD, PhD; Antin, Joseph H., MD; Lehmann, Leslie, MD; Shore, Tsiporah, MD; Iacobelli, Massimo, MD; Miloslavsky, Maja, PhD; Hume, Robin, MS; Hannah, Alison L., MD; Nejadnik, Bijan, MD; Soiffer, Robert J., MD
Biology of blood and marrow transplantation, 06/2017, Letnik: 23, Številka: 6Journal Article
Highlights • Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) can be severe. • Severe VOD/SOS may be associated with multi-organ dysfunction and ≥80% mortality. • Defibrotide has demonstrated efficacy in treatment of severe hepatic VOD/SOS. • This has been the largest prospective evaluation of defibrotide for severe VOD/SOS.
