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Johnstone, D.M; el Massri, N; Moro, C; Spana, S; Wang, X.S; Torres, N; Chabrol, C; De Jaeger, X; Reinhart, F; Purushothuman, S; Benabid, A.-L; Stone, J; Mitrofanis, J
Neuroscience, 08/2014, Letnik: 274Journal Article
Highlights • Near infrared light (NIr), directed transcranially, is neuroprotective in rodent models of neurodegeneration. • We assessed the neuroprotective efficacy of remotely-applied NIr in an MPTP mouse model of parkinsonism. • As with transcranial NIr, remote NIr protects dopaminergic cells from damage due to mild MPTP doses. • The findings have important implications for the clinical translation of light-based therapies.
