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Logan, R.W; McClung, C.A
Neuroscience, 05/2016, Letnik: 321Journal Article
Highlights • Pharmacological approaches to induce hyperactivity as a model of human mania have been used for many years. • Environmental manipulations are used to induce manic-like states which mimic multiple facets of this complex disorder. • Most recent studies have focused on genetic models. • Certain outbred strains of mice may be useful in modeling the polygenic nature of this disease. • Ultimately, models that cycle through various mood states are needed.
