Strongly interacting quark-gluon plasma (sQGP) is a state of nuclear matter at extremely high values of temperature with quarks and gluons as degrees of freedom. Jet-quenching is one of the evidences for sQGP formation in relativistic heavy ion collisions (A+A) and is manifested by suppression of particle yields at high transverse momentum relative to yields of the same particles measured at elementary proton-proton collisions at the same collision energy. Systematic experimental research of jet-quenching is provided by the measurement of nuclear modification factors of light mesons (π0, η, K s 0 , ω etc.) in different A+A systems. Asymmetric system of Cu+Au collisions at s NN =200 GeV is characterised by similar energy density but different collision geometry when compared to symmetric systems (Au+Au or Cu+Cu). This paper presents measurements of π0 and η mesons nuclear modification factors in Cu+Au collisions. Results are compared with ones measured in Au+Au and Cu+Cu collisions at the same collision energy.