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Seystahl, Katharina; Wick, Wolfgang; Weller, Michael
Critical reviews in oncology/hematology, 03/2016, Letnik: 99Journal Article
Highlights • Standards of care are incompletely defined in recurrent glioblastoma. • The evidence for repeat surgery or reirradiation is limited. • Alkylating chemotherapy (nitrosourea, temozolomide) is a widely accepted therapeutic option. • Bevacizumab has clinical activity, but an effect on overall survival is uncertain. • Individualized treatment concepts should consider age, performance status, MGMT promoter methylation status, response to and type of previous regimens and quality of life.
