Tuberculosis was a major health problem in Split between the two world wars. Scientific publications, journals, and local newspapers played an important role in health ducation as one of the preventive treatment methods of this nefarious disease, which is based on Štampar’s sociomedical ideas, as well as in shattering prejudices and raising popular awareness of how to face the consequences of the disease. This paper establishes the existence of a continuity in the creation of recorded public knowledge relevant to this topic, with particular reference to the role of mass media such as Novo doba and Jadranski dnevnik. Novo doba was a very important political-informative weekly newspaper published from 1918 until 22 April 1941. Jadranski dnevnik was published from 1934 to 1938. Both papers successfully performed their social function of providing information, shaping public opinion, and spreading knowledge, transferring all the complexity and necessity of modernisation practices that were changing Split and making it into a modern city. Among these modernisation practices was the struggle against tuberculosis as a serious socio-medical problem.