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Behavioural patterns in allergic rhinitis medication in Europe [Elektronski vir] : a study using 28 MASK-air® real-world dataSousa-Pinto, Bernardo ...Background. Co-medication is common among patients with allergic rhinitis (AR), but its dimension and patterns are unknown. This is particularly relevant since AR is understood differently across ... European countries, as reflected by rhinitis-related search patterns in Google Trends. This study aims to assess AR co-medication and its regional patterns in Europe, using real-world data. Methods. We analysed 2015-2020 MASK-air® European data. We compared days under no medication, monotherapy, and co-medication using the visual analogue scale (VAS) levels for overall allergic symptoms (“VAS Global Symptoms”) and impact of AR on work. We assessed the monthly use of different medication schemes, performing separate analyses by region (defined geographically or by Google Trends patterns). We estimated the average number of different drugs reported per patient within one year. Results. We analysed 222,024 days (13,122 users), including 63,887 days (28.8%) under monotherapy, and 38,315 (17.3%) under co-medication. The median “VAS Global Symptoms” was 7 for no medication days, 14 for monotherapy and 21 for co-medication (p<0.001). Medication use peaked during the spring, with similar patterns across different European regions (defined geographically or by Google Trends). Oral H1-antihistamines were the most common medication in single and co-medication. Each patient reported using an annual average of 2.7 drugs, with 80% reporting two or more. Conclusions. AR medication patterns are similar across European regions. One third of treatment days involved co-medication. These findings suggest that patients treat themselves according to their symptoms (irrespective of how they understand AR), and that co-medication use is driven by symptom severity.Source: Allergy [Elektronski vir]. - ISSN 1398-9995 (Vol. 77, iss. 9, Sep. 2022, str. 2699-2711)Type of material - e-article ; adult, seriousPublish date - 2022Language - englishCOBISS.SI-ID - 100821507
Author
Sousa-Pinto, Bernardo |
Sá-Sousa, Ana |
Vieira, Rafael José |
Amaral, Rita |
Klimek, Ludger |
Czarlewski, Wienczyslawa |
Antò i Boquè, Josep M. |
Pfaar, Oliver |
Bedbrook, Anna |
Zidarn, Mihaela |
Fonseca, Joao A. |
Bousquet, Jean
Topics
Asthma |
Drug therapy |
Rhinitis |
Drug therapy |
Rhinitis, allergic |
Drug therapy |
Visual analogue scale |
Histamine antagonists |
Astma |
Terapija z zdravili |
Rinitis |
Terapija z zdravili |
Alergijski rinitis |
Terapija z zdravili |
Vizualna analogna lestvica |
Histaminski antagonisti |
antihistamines |
behavioural patterns |
medication patterns |
real-world data |
antihistaminiki |
vedenjski vzorci |
vzorci zdravljenja |
podatki iz resničnega življenja
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Sousa-Pinto, Bernardo | |
Sá-Sousa, Ana | |
Vieira, Rafael José | |
Amaral, Rita | |
Klimek, Ludger | |
Czarlewski, Wienczyslawa | |
Antò i Boquè, Josep M. | |
Pfaar, Oliver | |
Bedbrook, Anna | |
Zidarn, Mihaela | 25317 |
Fonseca, Joao A. | |
Bousquet, Jean |
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