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Celični označevalci za opredelitev mieloičnih in limfatičnih novotvorb = Cell markers for determination of myeloid and lymphoid neoplasmsBitenc Logar, Darja ; Černelč, PeterKrvne celice imajo na svoji površini in v notranjosti različne antigene, ki služijo kot celični označevalci. Prisotnost teh molekul je odvisna od vrste in stopnje zrelosti celice. Celični označevalci ... imajo različno stopnjo vrstne specifičnosti. Imunofenotipizacijo omogočajo številna monoklonska protitelesa, ki so glede na antigen, ki ga določajo, razvrščena v CD (Cluster Designation) skupine. Z različnimi fluorokromi označena protitelesa določamo s pretočnim citometrom. Imunofenotipizacija je običajno večstopenjska. Z ustrezno kombinacijo protiteles lahko v večini primerov ločimo normalne, levkemične in limfomske celice. Imunofenotipizacija nezrelih levkemičnih in limfomskih celic je najpomembnejša preiskava za opredelitev podvrst akutne mieloične levkemije, akutne limfoblastne levkemije in malignih limfomov.Source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Let. 52, št. 4, 2001, str. 307-315)Type of material - article, component partPublish date - 2001Language - slovenianCOBISS.SI-ID - 1029745
Author
Bitenc Logar, Darja |
Černelč, Peter
Topics
celični označevalci |
CD |
mieolične novotvorbe |
limfatične novotvorbe |
pretočna citometrija
source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Let. 52, št. 4, 2001, str. 307-315)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Bitenc Logar, Darja | 20373 |
Černelč, Peter | 07012 |
Source: Personal bibliographies
and: SICRIS
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