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Preemptivna analgezija z metamizolom pri bolnikih, operiranih zaradi manjših programskih operacij = Pre-emptive analgesia with metamizol at the patients who were undergoing small, elective operations
Uranjek, Jasna ; Rus-Vaupot, Viktorija
Background. An acute postoperative pain is still a major medical, economic andalso societal problem. That is why so many studies are made, how to successfully prevent and treat post operative pain. ...Pre-emptive analgesia is one of the possibilities. The aim of our study was to evaluate the use of pre-emptive analgesia with metamizol intravenously with patients who were undergoing small, elective operations (stripping, removal of the osteosynthetic material, arthroscopy of the knee and sterilisation). Patients and methods. The study was accepted by the Republic Medical Ethical Commission. All included patients agreed with the participation in the study. 40 patients scheduled for minor operations were randomly assigned to group A and group B. Patients in group A received 2.5g metamizol intravenously 15 min.before induction to anaesthesia and group B received 2.5g metamizol at least 5 min. after surgical incision. Anaesthesia in both groups was maintained with the mixture of anaesthesiological gases 02:N20(50:50) and isofluorane or halothane. Preoperatively the patients were asked about their expectation of pain postoperatively, about their previous experiences of postoperative pain, preoperative use of analgesics and their subjective opinion about their pain threshold. Postoperatively, pain scores with visual analogue scale VAS (1-10), blood pressure, pulse and side effects were recorded every three hours for the first 24 hours after the surgery. Patients were told that they will get supplemental analgesic if the value of VAS was 4 or more. Results and discussion. VAS scores were statistically significant lower in group A (t = 2.9, p<O.O5; variances tested with F test) then in groupB but in both groups they were in satisfying limits (VAS 1-3). Also the use of supplemental analgesics during and after the surgery was lower in groupA. Conclusions. Both administrations of metamizol provide satisfying results. (Abstract truncated at 2000 characters.)
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