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Novejši stabilizatorji razpoloženja = New mood stabilizers
Jordanova, Vesna ; Dernovšek, Mojca Zvezdana
Bipolar affective disorder is characterized by more or less rapid changing of manic and depressive episodes. This cycling can be slowed down or prevented with some drugs, which are called mood ...stabilizers. Besides older and well-established drugs like lithium and carbamazepine, some new drugs have recently been introduced. These drugs mostly belong to a group of antiepileptics (sodium valproate, lamotrigine, gabapentine, clonazepam), calcium channel antagonists (verapamil, nimodipine, nifedipine) and atypical antipsychotics (risperidone, olanzapine, clozapine). This paper deals with basics of pharmacodynamics and pharmacokinetics of mentioned newer drugs and gives numerous hints for their use in practice.
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