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Polyploidization and cancer [Elektronski vir]Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, ... inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relatiType of material - e-bookPublication and manufacture - New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2010Language - englishISBN - 978-1-4419-6199-0; 1-4419-6199-2COBISS.SI-ID - 1543162847
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SpringerLink e-books 2008-2012Celotno besedilo dostopno za uporabnike SpringerLink slovenskega konzorcija neprofitnih institucij
Full text accessible to the users of SpringerLink Slovenian Consortium of Non-Profit Institutions
DOI
Other authors
Poon, Randy Y. C.
Topics
Cancer |
Genetic aspects |
Polyploidy |
Neoplasms |
genetics |
Chromosomal Instability |
genetics |
Gene Expression Regulation, Neoplastic |
genetics |
Polyploidy |
Medicine |
Biomédecine |
Sciences de la vie |
Cancer |
Genetic aspects |
Polyploidy |
HEALTH & FITNESS |
Diseases |
Cancer |
MEDICAL |
Oncology |
Electronic books
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