ALL libraries (COBIB.SI union bibliographic/catalogue database)
  • Fetal death from SARS-CoV-2 mediated acute placental failure [Elektronski vir]
    Kosič, Nadja ...
    Introduction We demonstrate the nonlinear severity of symptoms of SARS-CoV-2 infection in the mother leading to fetal death after acute placental failure. Methods Careful clinical evaluation, ... real-time RT-PCR molecular microbiologic testing, isolation of a viable virus, and autopsy with histologic results were used to investigate the possible vertical transmission of SARS-CoV-2 infection from mother to fetus. Results Histologic changes in the placenta correlate with SARS-CoV-2 infection. Total nucleic acid isolated from vaginal swabs, fresh placental tissue, and deparaffinized tissue showed a high viral load of SARS-CoV-2. Complete genome sequencing confirmed the presence of the SARS-CoV-2 Delta variant. Discussion Several methods have been used to confirm SARS-CoV-2-mediated acute placental failure, all of which were conclusive. It should be noted that careful periodic fetal well-being checks are required in women infected with SARS-CoV-2, regardless of the severity of symptoms. Most of the cases described with fetal death occurred in the third trimester.
    Source: Journal of Reproductive Immunology [Elektronski vir]. - ISSN 1872-7603 (Vol. 158, [article no.] 103958, 2023, str. 1-5)
    Type of material - e-article
    Publish date - 2023
    Language - english
    COBISS.SI-ID - 154593539

    Link(s):

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191722/
    Repository of the University of Ljubljana – RUL
    DOI

Shelf entry