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Solid-phase synthesis of amidines by the reduction of amidoximes
Cesar, Jožko ; Nadrah, Kristina ; Sollner Dolenc, Marija
Amidines can be prepared on a solid support by reducing polymer-bound amidoximes with SnCl2 2H2O. The method has proved to be straightforward and highly efficient. Amidoximes attached to the solid ...support are readily available by treating resin-bound nitriles with hydroxylamine.
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