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Izkustveno antibiotično zdravljenje sepse pri otroku = Empirical antibiotic treatment of sepsis in children
Čižman, Milan ; Ahčan, Jerneja
Sepsis is an infection-induced syndrome defined as the presence of signs of infection and features of systemic inflammatory response. The incidence of septicemia is highest in the neonatal period and ...the case-fatality rate is highest in children below one year of age. The etiologic agents responsible for septicemia vary according to age and immunological status of the patient and the setting of microbial acquisition (i.e., community or hospital). Early diagnosis and prompt administration of antimicrobial agents are essential in the treatment of sepsis. The initial antibiotic therapy is almost always empirical, bactericidal antibiotics etiher alone or combined in high dosages are given parenterally. The authors review empirical antibiotic treatment of systemic infections in different age groups, with regard to potential sources of infection, setting of infection acquisition and duration of treatment.
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