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  • Cellular diagnostic arrays, methods of using and processing for producing same
    Bitensky, Mark W. ...
    A cellular diagnostic array has been developed that provides accurate and reproducible measurements of the physical parameters of individual cells en masse, including cell membrane surface area, cell ... volume, and excess membrane.Three differing patterns are employed. In the first design, a gradient array having rectangular shaped channels is used to capture cells andreadily show the ratio of volume to surface area for the captured cell. Thesecond silicone rubber array provided by the present invention employs an array of wedge shaped pipettes, each of which captures an individual cell. Theposition of the cell within a wedge is enough to rapidly determine the cell's actual surface area and volume. A third type of cellular diagnostic array according to the present invention employs an array of channels designedto deform a cell to study how well the cell responds to repeated deformations.
    Type of material - patent
    Edition - April 24, 2007
    Publication and manufacture - United States Patent Application, 2007
    Language - english
    COBISS.SI-ID - 16644313

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