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Tarčno zdravljenje slovenskih bolnikov z razsejanimi gastrointestinalnimi stromalnimi tumorjiUnk, Mojca ...Klasifikacija, diagnostika in zdravljenje stromalnih ter mezenhimskih neoplazem prebavil je v zadnjih 30 letih doživela obsežen napredek. Gastrointestinalni stromalni tumorji (GIST) predstavljajo ... manj kot 1 % vseh malignih tumorjev prebavil.Klinična slika je odvisna od mesta, velikosti in malignega potenciala GIST. Razsejani GIST predstavlja primer uspešnega zdravljenja s tarčno terapijo, saj se je z odkritjem KIT in PDGFR signalne poti ter tirozin kinaznih inhibitorjev, kot staimatinib mesilat in sunitinib, prognoza te bolezni pomembno izboljšala. Izhod zdravljenja slovenskih bolnikov z razsejanim GIST je primerljiv z izhodom zdravljenja bolnikov, ki so bili zdravljeni v pomembnih večjih mednarodnih kliničnih raziskavah, srednji čas do progresa bolezni pri naših bolnikih je 52 mesecev in srednje preživetje 72 mesecev. Uporabljali smo protokol sledenja, ki je poleg kontrastne računalniške tomografije trebuha vključeval tudi preiskavo trebuha z ultrazvokom. S tem smo ob primerljivem preživetju izboljšali kakovost življenja naših bolnikov in zmanjšali stroške zdravljenja.Source: Onkologija : strokovni časopis za zdravnike. - ISSN 1408-1741 (Letn. 17, št. 2, dec. 2013, str. 84-86, 153)Type of material - article, component partPublish date - 2013Language - slovenianCOBISS.SI-ID - 1679739
source: Onkologija : strokovni časopis za zdravnike. - ISSN 1408-1741 (Letn. 17, št. 2, dec. 2013, str. 84-86, 153)
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Unk, Mojca | 34807 |
Matos, Erika | 20055 |
Eržen, Darja, 1952- | 14441 |
Zakotnik, Branko | 11747 |
Source: Personal bibliographies
and: SICRIS
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