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  • The Importance of acromegaloid physical features for clinical practice [Elektronski vir] : case report
    Perić, Ivona ...
    Acromegaly and gigantism are hormonal disorders which develop as a consequence of chronic growth hormone hypersecretion. Te prefx pseudo- is used to describe a certain clinical condition without a ... clearly proven characteristic of pathophysiological mechanism and basic biochemical features; pseudoacromegaly or acromegaloidism match the defnition from above. In this case reports, we will try to provide a concise overview of diagnostic evaluation of acromegaloid physical appearance, while discussing two cases of patients who have similar clinical acromegaloid features as the frst sign of the disease but have completely diferent etiologic backgrounds of their acromegalic appearance. Te frst case is of a 57-year-old male who presented with a marked acral growth and coarse facial features, but the diagnosis of secondary amyloidosis caused by multiple myeloma was confrmed just after biopsy of tongue and buccal mucosa. Te second case is that of a 63-year-old male with an acromegaloid appearance caused by ectopic secretion of GH secreting lung carcinoma. Te early diagnosis of ectopic acromegaly and pseudoacromegaly is still a challenging process. Te key task is to confrm the GH axis abnormalities and establish the underlying disease, as a crucial step for faster treatment and need to avoid unnecessary therapeutic procedures to decreased mortality and improved quality of life.
    Source: Case Reports in Endocrinology. - ISSN 2090-651X (Vol. 2023, [article no.] 5583344, 2023, Str. 1-6)
    Type of material - e-article ; adult, serious
    Publish date - 2023
    Language - english
    COBISS.SI-ID - 173718275

    Link(s):

    https://www.hindawi.com/journals/crie/2023/5583344/
    DOI

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