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  • Acute hyperglycemia and spatial working memory in adolescents with type 1 diabetes
    Šuput, Jasna ...
    Objective To investigate the effect of acute hyperglycemia on brain function in adolescents with type 1 diabetes (T1D). Research design and methods Twenty participants with T1D (aged 14.646 1.78 ... years) and 20 age-matched healthy control subjects (aged 14.4062.82 years) performed two functional MRI sessions. Participants with T1D performed the first scanning session under euglycemic and the second under hyperglycemic clamp (20 mmol/L [360 mg/dL]). Results Lower spatial working memory (sWM) capacity during acute hyperglycemia and significant differences in activation of regions of interest during different stages of the sWM task (P 5 0.014) were observed. Conclusions Acute hyperglycemia negatively affected sWM capacity in adolescents with T1D, which is relevant for daily functioning and academic performance
    Source: Diabetes care. - ISSN 0149-5992 (Vol. 43, no. 8, Aug. 2020, str. 1941-1944)
    Type of material - article, component part
    Publish date - 2020
    Language - english
    COBISS.SI-ID - 17753603

source: Diabetes care. - ISSN 0149-5992 (Vol. 43, no. 8, Aug. 2020, str. 1941-1944)
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