ALL libraries (COBIB.SI union bibliographic/catalogue database)
-
Medulllary thyroid carcinoma ; Genetic screening and prophylactic thyroidectomiesBergant, Damijan, 1951- ; Hočevar, Marko, 1964-Medullary thyroid cancer is a rare, neuroendocrine, tumor. It arises from parafollicular or C-cells with the ability to produce and secrete different bioactive substances like calcitonin (TC) and CEA ... (1-5) TC is ideal tumor marker in early diagnosis, in patents' follow up and in evaluation of their treatment. TC determinations after ca/pentagastrine stimulation test give us even more accurate results and the procedure is used for biochemical family screening 6'` MTC occurs as a sporadic tumor or in hereditary settings MEN 2A,MEN 2B and FMCT 3,4,8,9 Germ/line point mutations in RET proto/onkogene areresponsible for tumor arise and inheritance of settings. Genetic screening provides information of these RET mutations in family members even before pathologic changes occur. These individuals with MEN 2A, 2B and FMCT characteristic RET mutations are almost certain to acquire MTC (95% penetrance) in their lives and are candidates for preventive total thyroidectomy (TT), with or without central neck dissection (CND). Surgery is stilt the treatment of choice for MTC and only C-cell hyperplasia and early stage of MTC can be cured. Prophylactic thyroid surgery eliminates the possibilitv of MTC but doesn't influence appearance of other diseases (PHEO, HPTH) of MEN 2 syndromes 2,12-18.Source: Acta chirurgica Iugoslavica : časopis za hirurgiju Udruženja hirurga Jugoslavije. - ISSN 0001-5474 (Letn. 10, št. 3, 2003, str. 121-124)Type of material - article, component partPublish date - 2003Language - englishCOBISS.SI-ID - 18154969
source: Acta chirurgica Iugoslavica : časopis za hirurgiju Udruženja hirurga Jugoslavije. - ISSN 0001-5474 (Letn. 10, št. 3, 2003, str. 121-124)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Bergant, Damijan, 1951- | 08748 |
Hočevar, Marko, 1964- | 12023 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: