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Statin and fibrate treatment of combined hyperlipidemia: the effects on some novel risk factorsŠebeštjen, Miran ...The effects of cerivastatin and fenofibrate on proteins involved in haemostasis and on markers of inflammation were investigated in otherwise healthy middle-aged males with combined hyperlipidemia. ... Besides classical riskfactors, other so-called novel risk factors for coronary artery disease are seen to be playing an increasingly important role in the development and progression of atherosclerosis. Thirty-eight males, aged 49 5 years were randomised to 12 weeks treatment either with cerivastatin at a daily dose of 0.2 mg to 0.4 mg to achieve the LDL cholesterol goal of < 3.0 mM, or with fenofibrate 250 mg daily. Fasting serum lipids, homocysteine, total and free tissue factor pathway inhibitor (TFPI), plasminogen activator inhibitor (PAI-1) and tissue plasminogen activator (t-PA) antigen and activity, C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-alpha) were measured. (Abstract truncated at 2000 characters)Source: Thrombosis and haemostasis. - ISSN 0340-6245 (Letn. 92, 2004, str. 1129-1135)Type of material - article, component partPublish date - 2004Language - englishCOBISS.SI-ID - 18764249
Author
Šebeštjen, Miran |
Keber, Irena |
Žegura Andrić, Branka |
Simčič, Saša |
Božič, Mojca, 1970- |
Fressart, Migaud |
Stegnar, Mojca
Topics
Hyperlipidemia |
Drug Therapy |
Coronary Disease |
Prevention And Control |
Procetofen |
Antilipemic Agents |
Lipoproteins, Ldl Cholesterol |
Middle Age |
Risk Factors |
Blood Pressure |
Homocysteine |
Plasminogen Activator Inhibitor 1 |
Alteplase |
C-Reactive Protein |
Interleukin-6 |
Tumor Necrosis Factor |
Cholesterol |
Triglycerides |
Creatinine |
Lipoproteins, Hdl Cholesterol |
Hiperlipidemija |
Koronarna bolezen |
Lipolitiki |
Lipoproteini, LDL, holesterol |
Procetofen |
C-reaktivna beljakovina |
Dejavniki tveganja |
Holesterol |
Homocistein |
Interlevkin-6 |
Kreatinin |
Krvni pritisk |
Lipoproteini, HDL, holesterol |
Plazminogen aktivator, inhibitor 1 |
Srednja leta |
Trigliceridi |
Tumor nekrotizirajoči faktor
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Šebeštjen, Miran | 19345 |
Keber, Irena | 00365 |
Žegura Andrić, Branka | 21099 |
Simčič, Saša | 05382 |
Božič, Mojca, 1970- | 15637 |
Fressart, Migaud | |
Stegnar, Mojca | 05034 |
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