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Organ-sparing techniques and dose-volume constrains used in breast cancer radiation therapy [Elektronski vir] : results from European and Latin American surveysChirilǎ, Monica Emilia ...Background: Advances in local and systemic therapies have improved the outcomes of patients with breast cancer (BC), leading to a possible increased risk for postoperative radiation therapy (RT) late ... adverse events. The most adequate technologies and dose constraints for organs at risk (OAR) in BC RT have yet to be defined. Methods: An online survey was distributed to radiation oncologists (ROs) practicing in Europe and Latin America including the Caribbean (LAC) through personal contacts, RO and BC professional groups’ networks. Demographic data and clinical practice information were collected. Results: The study included 585 responses from ROs practicing in 57 different countries. The most frequently contoured OAR by European and LAC participants were the whole heart (96.6 % and 97.7 %), the ipsilateral (84.3 % and 90.8 %), and contralateral lung (71.3 % and 77.4 %), whole lung (69.8 % and 72.9 %), and the contralateral breast (66.4 % and. 83.2 %). ESTRO guidelines were preferred in Europe (33.3 %) and the RTOG contouring guideline was the most popular in LAC (62.2 %), while some participants used both recommendations (13.2 % and 19.2 %). IMRT (68.6 % and 59.1 %) and VMAT (65.6 % and 60.2 %) were the preferred modalities used in heart sparing strategies, followed by deep inspiration breath-hold (DIBH) (54.8 % and 37.4 %) and partial breast irradiation (PBI) (41.6 % and 24.6 %). Only a small percentage of all ROs reported the dose-volume constraints for OAR used in routine clinical practice. A mean heart dose (Heart-Dmean) between 4 and 5 Gy was the most frequently reported parameter (17.2 % and 39.3 %). Conclusion: The delineation approaches and sparing techniques for OAR in BC RT vary between ROs worldwide. The low response rate to the dose constraints subset of queries reflects the uncertainty surrounding this topic and supports the need for detailed consensus recommendations in the clinical practice.Source: Clinical and translational radiation oncology. - ISSN 2405-6308 (Vol. 46, May 2024, str. 100752-1-100752-8)Type of material - e-article ; adult, seriousPublish date - 2024Language - englishCOBISS.SI-ID - 189336835
Author
Chirilǎ, Monica Emilia |
Kraja, Fatjona |
Nader Marta, Gustavo |
Neves Junior, Wellington Furtado Pimenta |
Arruda, Gustavo Viani de |
Guimarães Gouveia, André |
Franco, Pierfrancesco |
Poortmans, Philip |
Ratoša, Ivica
Topics
rak dojke |
dozni volumen |
ohranitev srca |
radioterapija |
breast cancer |
dose volume constraints |
heart sparing |
radiotherapy
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Chirilǎ, Monica Emilia | |
Kraja, Fatjona | |
Nader Marta, Gustavo | |
Neves Junior, Wellington Furtado Pimenta | |
Arruda, Gustavo Viani de | |
Guimarães Gouveia, André | |
Franco, Pierfrancesco | |
Poortmans, Philip | |
Ratoša, Ivica | 34883 |
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