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Povezava med zgornjim uvajanjem jajčnega rumenjaka v otrokovo prehrano in pojavom atopijskega dermatitisa v starosti 18 mesecev = Relationship between early exposure to egg yolk and atopic dermatitis in 18 months old childrenBesednjak-Kocijančič, Lilijana, dr. med.Background. Atopic eczema/dermatitis syndrome (AEDS) is the most frequent inflammatory disease of the skin in the childhood. A cause-effect link betweenfood allergy and atopic dermatitis (AD) has ... been established and sensitization to hen's egg is considered a strong predictor for AD. Egg yolk is usually introduced into the child's diet in the first year. The purpose of this study was to assess the influence of early introduction of egg yolk into the diet on AD prevalence in 18 month old children. Methods. 269 infants with birth weight at least 3000 g and with a positive history ofparental allergy confirmed by allergy testing were included. They were divided in three groups according their age at the introduction of boiled egg into the child's diet: group A - children eating egg yolk from 6 month; group B - children eating eggyolk from month; group C children eating egg yolk from 12 month. Children from all groups were exclusively breast fed for at least 6 month while their mothers were on a diet without eggs. The diagnosis of AD was made according tothe criteria of Hanifin and Rajka. At 18 months of age sensitization to egg yolk was evaluated with specific IgE testing and skin prick test (SPT). Statistical analysis was performed with SPSS 10.0 using the Mantel-Haenszel chi-square test. Results. In group A 57.1%, group B 31.7% and in group C 21.3%of children developed AEDS (p < 0.0001). Elevated serum total IgE had 58.9% of children from group A, 34.1% from group B and 18.7% from group C (p <0.0001). Elevated specific IgE antibodies to egg yolk had 25.0% of children from group A, 12.2% from B and 6.7% from C (p = 0. 001). Positive SPT with eggyolk had in group A 37.5%, B 23.1% and C 18.7% of children with AD (p = 0. 099). Conclusions. We demonstrated a negative influence of early introduction of egg yolk into the diet on AD and AEDS prevalence in a group of newborns at risk for atopic diseases.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 1, 2005, str. 23-26)Type of material - article, component partPublish date - 2005Language - slovenianCOBISS.SI-ID - 19018457
Author
Besednjak-Kocijančič, Lilijana, dr. med.
Topics
Infant Nutrition |
Egg Yolk |
Dermatitis, Atopic |
Skin Tests |
IgE |
Food Hypersensitivity |
Prospective Studies |
Infant |
Dermatitis atopični |
Dojenček, prehrana |
IgE |
Jajce, rumenjak |
Kožni testi |
Dojenček |
Hrana, preobčutljivost |
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