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The dimethylhydrazine induced colorectal tumours in rat - experimental colorectal carcinogenesis = Z dimetilhidrazinom inducirani tumorji debelega črevesa in danke pri podganiPerše, Martina, 1975- ; Cerar, Anton, 1945-Animal models of colorectal carcinogenesis represent invaluable research tool for investigating colorectal cancer (CRC). Experimentally induced tumours in laboratory animals provide opportunity for ... studying certain aspects of tumoursthat cannot be effectively studied in humans. Significant information on human CRC aetiology or factors influencing it has derived from studies using dimethylhydrazine (DMH) model that is one of the experimental models appreciated for its morphological similarity to human CRC. Today, DMH model represents useful research tool for the studies of colon carcinogens and chemopreventive agents. The review offers insight into morphogenesis and genetic alterations of DMH induced colorectal epithelial tumours in rats.Source: Radiology and oncology. - ISSN 1318-2099 (Letn. 39, št. 1, 2005, str. 61-70)Type of material - article, component partPublish date - 2005Language - englishCOBISS.SI-ID - 19252953
Author
Perše, Martina, 1975- |
Cerar, Anton, 1945-
Topics
Colorectal Neoplasms |
Chemically Induced |
Pathology |
Dimethylhydrazines |
Adenoma |
Adenocarcinoma |
Disease Models, Animal |
Rats, Inbred F344 |
Rats, Sprague-Dawley |
Rats, Wistar |
Adenokarcinom |
Adenom |
Dimetilhidrazini |
Kolorektalne novotvorbe |
Bolezen, živalski modeli |
Miši seva F344 |
Podgane, Sprague-Dawley |
Podgane, Wistar
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Perše, Martina, 1975- | 23082 |
Cerar, Anton, 1945- | 05367 |
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