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Vpliv kemičnih motilcev endokrinega sistema na epigenetiko in delovanje jajčnika = Effect of endocrine disrupting chemicals on epigenetics and ovarian functionKek, Tina ; Videtič Paska, Alja, 1980- ; Geršak, KsenijaLjudje smo vsakodnevno izpostavljeni različnim kemičnim motilcem endokrinega sistema (KMES). Izpostavljenost KMES je povezana s številnimi motnjami in boleznimi reproduktivnega sistema, vendar njihov ... vpliv še ni natančno pojasnjen. Opisanih je več različnih mehanizmov preko katerih KMES lahko motijo delovanje organizma. Reproduktivno zdravje je odvisno od pravilnega prenatalnega razvoja jajčnikov, ki je ključen za njihovo pravilno delovanje. Ugotovitve epidemiolo-ških študij in študij na živalih kažejo, da prenatalna izpostavljenost KMES lahko povzroči različne bolezni reproduktivnega sistema pozneje v življenju, kar povzema hipoteza sindroma ovarijske disgeneze. Eden od vzročnih mehanizmov delovanja KMES za pojav sindroma ovarijske disgeneze naj bi bile tudi epigenetske spremembe. V članku, ki je pregled literature na tem področju, je predstavljena vloga epigenetskih procesov (DNA metilacija, ne-kodirajoča RNA, histonske modifikacije) v toksičnem delovanju KMES na reproduktivni sistem.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 93, št. 3/4, mar./apr. 2024, str. 121-134)Type of material - article, component part ; adult, seriousPublish date - 2024Language - slovenianCOBISS.SI-ID - 193328387
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source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 93, št. 3/4, mar./apr. 2024, str. 121-134)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Kek, Tina | 55945 |
Videtič Paska, Alja, 1980- | 27742 |
Geršak, Ksenija | 00814 |
Source: Personal bibliographies
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