ALL libraries (COBIB.SI union bibliographic/catalogue database)
  • Residual melanoma after an excisional biopsy is an independent prognostic factor for local recurrence and overall survival
    Hočevar, Marko, 1964- ...
    The aim of this study was to evaluate the effect of a residual melanoma after an excisional biopsy on prognosis of patients with cutaneous melanoma. PATIENTS AND METHODS: Between 2000 and 2007 ... sentinel lymph node biopsy with wide reexcision of a primary melanoma site was successfully performed in 692 patients (315 male and 377 female; mean age 55.7 years) at the Institute of Oncology Ljubljana, Slovenia. Clinicopathological data of all patients were extracted from a prospective institutional melanoma database and the frequency of local recurrences and survival were compared between patients with residual melanoma and those without it. For a statistical analysis univariate and multivariate analyses were used. RESULTS: Only 25 (3.6%) patients had a residual melanoma. There was no difference in mean tumor thickness (3.9 and 2.8 mm) and ulceration (40% and 34%) of the primary melanoma between patients with and without residual melanoma. However, a number of local recurrences (16% versus 2.7%) and a number of metastases in sentinel lymph nodes (44% versus 22%) were significantly higher and a 5-year survival was significantly lower (64% versus 87.5%) in patients with residual melanoma. Breslow thickness, ulceration, positive SLNB and residual melanoma were independent prognostic factors for overall survival. CONCLUSIONS: Residual melanoma is very rare after an excisional biopsy of the primary melanoma. However, when present it indicates a higher probability of local recurrence and a worse overall survival.
    Source: European journal of surgical oncology. - ISSN 0748-7983 (Vol. 40, no. 10, Oct. 2014, str. 1271-1275)
    Type of material - article, component part
    Publish date - 2014
    Language - english
    COBISS.SI-ID - 1937787
    DOI

source: European journal of surgical oncology. - ISSN 0748-7983 (Vol. 40, no. 10, Oct. 2014, str. 1271-1275)
loading ...
loading ...
loading ...

Shelf entry