ALL libraries (COBIB.SI union bibliographic/catalogue database)
13.
Comparison of intravenous ganciclovir and cytomegalovirus hyperimmune globulinpre-emptive treatment in cytomegalovirus-positive heart transplant recipients
Vrtovec, Bojan, 1972- ...
We compared the use of intravenous ganciclovir and cytomegalovirus hyperimmuneglobulin (CMVIG) as a pre-emptive treatment for cytomegalovirus (CMV)-positive heart transplant recipients. Of 59 ...CMV-seropositive adult hearttransplant recipients enrolled in Group 1,37 tested positive for pp65 antigen within 12 weeks post-transplantation. These patients were randomized to receive either intravenous ganciclovir (n = 23) or CMVIG (n = 14). Group 2 included 133 CMV-seropositive heart transplant recipients who were not tested for CMV antigenemia and who received no anti-CMV therapy. CMV disease developed in 0 of 59 patients from Group 1, and in 27 of 133 patients (20%) inGroup 2 (p = 0.0001). The incidence of superinfections was lower in Group 1 (0.28 0.46) than in Group 2 (1.10 1- 1.33) (p = 0.01). The 2 groups did not differ with regard to incidence of rejection (0.7 0.9 in Group 1 vs 1.0 1.2 in Group 2; p = NS), transplant coronary artery disease at 1 year (14% in Group 1 vs 16°/ in Group 2; p = NS) or post-transplant lymphoproliferative disease (0% in Group 1 vs 2% in Group 2; p = NS). Ganciclovir and CMVIG therapies were associated with similar rates of rejection (0.52 0.6 with ganciclovir vs 0.50 0.60 with CMVIG; p = NS), superinfection (0.30 0.48 with ganciclovir vs 0.25 0.46 with CMVIG; p = NS), and transplant coronary artery disease at 1 year <13% with ganciclovir vs 14% with CMVIG, p = NS). Thepre-emptive anti-CMV approach is superior to prophylaxis in CMV-seropositive heart transplant recipients. Both ganciclovir and CMVIG are equally effective. J Heart Lung Transplant 2004;23:461-465.
It was not necessary to add the material to the shelf.
Bibliographic material was successfully added on shelf.
Adding bibliographical material on shelf was not successful.
Material is already on the shelf.
Permalink
URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year
Impact factor
Edition
Category
Classification
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Select the library membership card:
DRS,
in which the journal is indexed
Database name
Field
Year
Links to authors' personal bibliographies
Links to information on researchers in the SICRIS system
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
