ALL libraries (COBIB.SI union bibliographic/catalogue database)
-
Mapping of central visual function in Best's vitelliform dystrophy = Ocena delovanja centralne mrežnice pri Bestovi viteliformni distrofijiJarc-Vidmar, Martina ...Best vitelliform dystrophy is the second most common inherited macular dystrophy, which usually starts at an early age and progressively affects the patient's central vision. In this clinically ... heterogenous and pleomorphic disease, ophthalmoscopic lesions often do not correspond with a deterioration of the visual function. The aim of our study was to investigate the presence of UMD2 mutation in our patients with Best's dystrophy and to evaluate retinalsensitivity and fixation patterns with retinal morphology. Blood samples of 11 patients trom five families with different stages of BVD were taken for genetic analysis. The central 10° visual fields were tested with static perimetry (Octopus M2 TOP) and microperimetry (MP1, Nidek Technologies). The results of MP testing were compared with retinal morphologyseen by autofluorescence (AF). In the initial stages. localised areas of hyperfluorescence centrally in the fovea, later became non-homogenous, finally being replaced by central hypofluorescent areas surrounded by hypertluorescent rings. Patients were divided into three groups.In the first two groups (VA: 0.8+-0.1 and 0.5+-0.3), patients fixated centrally adjacent to the relative (Group 1) or absolute (Group 2) scotoma inside a non-uniform hypo-and hyperfluorescent area. With disease progression,an evident shift of fixation to the preferential retinal locus (PRL) appeared in 8 eyes with a visual acuity of 0.2 or less (Group 3), PRL was never inside the central uniform hypofluorescent area but corresponded to the hyperfluorescent ring. A high correlation was found between MP and static perimetry (MS,MD and CLV indices): r= 0.75,-0.76 and-0.48. MP appears to be superior to static perimetry, with an important ability of fundus controlled fixation screening. A new G15R mutation was found in exon 2 of the VMD2 gene in the family M. Our results show a good correlation between morphology and visual function. (Abstract truncated at 2000 characters)Source: Molekularna diagnostika v medicini : zbornik predavanj = Molecular diagnostics in medicine : proceedings (Str. 231-239)Type of material - conference contributionPublish date - 2005Language - englishCOBISS.SI-ID - 20368089
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Jarc-Vidmar, Martina | 16364 |
Šlajpah, Maja | 21598 |
Popović, Petra, 1969- | 18375 |
Glavač, Damjan | 09275 |
Hawlina, Marko | 09154 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: