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Vpliv nadzorovane podhladitve na zdravljenje bolnikov po srčnem zastoju = Effect of induced hypothermia on treatment of patients after cardiac arrest
Grošelj, Urh ...
Induced hypothermia opened the possibility of effective causal prevention of neurological damage atter primary cardiac arrest. Induced hypothermia has beenused as a standard treatment at the Center ...for Intesive Internal Medicine (CIIM) since year 2004. The purpose of our study was to evaluate the survival,neurological outcome and safety of induced hypothermia. We included patients who were treated at the CIIM in the period from 1 January 2001 to 31 December 2005 tollowing primary cardiac arrest. All enrolled patients fulfilled the criteria for treatment with induced hypothermia. The test group consisted of all patients treated after 1 January 2004, when induced hypothermia was adopted as the standard treatment method and the control groupIncluded all other patients from the observed time period. Survival and long-term neurological outcomes were compared, as well as the rate of complications. The final analysis included 159 patients, of whom 85 had been treated with hypothermia and 74 were control subjects. The two patient groups were comparable in terms of their basic characteristics and treatment (with the exception of induced hypothermia). After half a year, 52% of patients who had been treated with hypothermia and 30% of those from the control group had a favorable neurological outcome (p < 0,01). In this period, 40% of patients treated with hypothermia and 60% of those from the control group died (p = 0,01). None of the treatment complications showed statistically significant deviations in incidence between the two groups. Induced hypothermia improves neurological outcomes and survival and does not increase the incidence of treatment complications in patients after cardiac arrest treated at the CIIM.
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