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Nadzorovana podhladitev upočasni kratkoročni nevrološki napredek pri bolnikih po srčnem zastoju = Induced hypothermia prolongs short term neurological recovery in patients after resuscitated cardiac arrest
Kavčič, Marko, medicina ...
In cardiac arrest (pVT/VF) survivors who remain comatose, the decision of withholding of the active treatment may be based on the clinical neurological examination 7 days after resuscitation. The ...purpose of our study was to evaluate yet unpublished clinical observations on slower neurological recoveryof patients who undergo hypothermia during their treatment after cardiac arrest. We included patients who were treated at the CIIM in the period from 1 st January 2001 to 31 st December 2005 following primary cardiacarrest. All enrolled patients fulfilled the criteria for treatment withcontrolled hypothermia. The test group consisted of patients treated after1 )anuary 2004 when induced hypothermia was adopted as the standard treatment method. Control group Included all other patients from the observed time period. The median time (25th, 75th percentile) to response was 3 days (2-5) in the hypothermic group, compared with 1,5 days (1-3) in the control group (P<0,01). The median time (25th, 75th percentile) to meaningful responsewas 4,25 days (3-6) in the hypothermic group, compared with 2 days (1-3) in the control group (P< 0,01). In patients who regain consciousness, neurological recovery is slower in patients treated with hypothermia.
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