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Uporaba NT-proBNP pri bolnikih s srčnim popuščanjem = Use of NT-proBNP in patients with heart failureMaver, JericaBNP (brain natriuretic peptide, B-type natriuretic peptide) has diuretic, natriuretic and vasodilating effects. The precursor of a biologically active form is produced in cardiac myocytes of both ... ventricles. NT-proBNP and active molecule BNP are released into blood. In healthv subjects their concentration in blood is low; however, it inereases markedly in congestive heart failure asa result of increased myocardial stretch. Serum concentrations of BNP and NT-proBNY are correlated to the degree of myocardial damage and to NYHA class.BNP and NT-proBNP have very good negative predictive value for ruling out acute heart failure as a cause of acute dyspnea. Increased serum concentrations of BNP and NT-proBNP contribute to diagnosing congestive heart failure and left ventricle dysfunction. They also carry prognostic informationin congestive heart failure. After successful treatment of congestive heart failure serum BNP and NT-proBNP decrease. Currentlv, BNP and NT-proBNP are not yet routinely used in everyday clinical practice for treatment monitoring in patients with congestive heart failure.Source: Zbornik predavanj : [interna medicina 2006 : novosti in aktualnosti] (Str. 251-254)Type of material - conference contributionPublish date - 2006Language - slovenianCOBISS.SI-ID - 21790937
Author
Maver, Jerica
Topics
Heart Failure, Congestive |
Natriuretic Hormone |
Prognosis |
Natriuretični hormon |
Prognoza |
Srce, odpoved kongestivna
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