ALL libraries (COBIB.SI union bibliographic/catalogue database)
-
Lipopolysaccharide-binding protein, lipopolysaccharide, and soluble CD14 in sepsis of critically ill neonates and childrenPavčnik Arnol, Maja, medicina, 1974- ; Hojker, Sergej ; Derganc, MetkaObjective: To compare the diagnostic accuracy of lipopolysaccharide-binding protein (LBP) for sepsis in critically ill neonates and children with the two markers participating in the same ... inflammatory pathway, lipopolysaccharide andsoluble CD14. Design and settings: Prospective, observational study in a multidisciplinary neonatal and pediatric intensive care unit. Patients: 47 critically ill neonates and 49 critically ill children with systemic inflammatory response syndrome (SIRS) and suspected sepsis, classified into two groups: those with and those without sepsis. Interventions: Serum LBP, lipopolysaccharide, soluble CD14, C-reactive protein, and procalcitonin were measured on 2 consecutive days. The area under the receiver operating characteristic curve (AUC), sensitivity, specificity, and predictive values were evaluated. Results: AUC for LBP on the first day of suspected infection was 0.97 in neonates aged under 48h, 0.93 in neonates over 48h and 0.82 in children. AUCs for lipopolysaccharide and soluble CD14 were 0.77 and 0.74 in neonates under 48h, 0.53 and 0.76 in neonates over 48h, and 0.72 and 0.53 in children. AUCs for procalcitonin and C-reactive protein were 0.65 and 0.89 in neonates under 48h, 0.65 and 0.91 in neonates over 48h, and 0.76 and 0.69 in children. Conclusions: In critically ill neonates and children LBP concentration on the first day of suspected sepsis is a better marker of sepsis than lipopolysaccharide, solubleCD14, procalcitonin, and in neonates younger than 48 hand children, also a better marker than C-reactive protein. Lipopolysaccharide and soluble CD14 are not suitable markers for the differentiation of infectious and noninfectious SIRS.Source: Intensive care medicine. - ISSN 0342-4642 (Letn. 33, št. 6, 2007, str. 1025-1032)Type of material - article, component partPublish date - 2007Language - englishCOBISS.SI-ID - 22467289
Author
Pavčnik Arnol, Maja, medicina, 1974- |
Hojker, Sergej |
Derganc, Metka
Topics
Sepsis |
Critical Illness |
Lipopolysaccharides |
Antigens, Cd14 |
Protein Binding |
Infant, Newborn |
Child |
Antigeni, CD14 |
Beljakovine, vezava |
Kritična bolezen |
Lipopolisaharidi |
Sepsa |
Novorojenček |
Otrok
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Pavčnik Arnol, Maja, medicina, 1974- | 22349 |
Hojker, Sergej | 01900 |
Derganc, Metka | 02148 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: