ALL libraries (COBIB.SI union bibliographic/catalogue database)
13.
Rast glave pri otrocih z infantilnimi spazmi
Krivec, Uroš, 1975- ; Lozar Krivec, Jana
BACKGROUND Infantile spasms (lS) begin in a very active phase of brain development. Since changes in head circumference (HC) accurately reflect changes in brain growth during infancy, we assumed the ...possibility that epileptic activity which interferes with brain development would also lead to head growth failure in children affected by IS. The aim of the study was to determine the relationship between outcome and HC at different age or different time after onset of IS. PATIENTS AND METHODS The sfudy involved 38 children (17 boys and 21 girls) with history of IS and no other obvious cause for an abnormal head growth (i.e. hydrocephalus, chromosomal or genetic abnormality). The data for HC were gathered from patientsć medical documentation. HCs below the 10th percentile of Slovene population were considered abnormal. In terms of cognitive and neuro-developmental outcome thechildren were grouped into four categories (1-normal to 4-sever impairment). t-test and multiple linear regression were used to test the relationship between HC and outcome. RESULTS Abnormal HC in the 4th and the 5th month after onset of spasms was significantly associated with abnormal mental development ( 2.8 vs.1.7, p= 0.004). This relation persisted even when several factors like etiology, duration of spasms, gestational age and delayeddevelopment before onset of spasms were controlled. In the 4th month after onset of spasms normal mental development was present in only 12% (1Č8) of children with abnormal head size. The mean HC of the children with IS was not significantly lower than the mean HC in normal population, eventhough the proportion of the children with abnormal head size (27%) was larger. CONCLUSIONS It was found that HC represents an important predictive factor forcognitive outcome in children with history of IS. Since HC can be measured quickly and easily its considerable predictive role in follow up should not beignored in any children and specially not in those with IS.
Type of material - research report
Publication and manufacture - Ljubljana : [U. Krivec] : [J. Lozar], 2000
It was not necessary to add the material to the shelf.
Bibliographic material was successfully added on shelf.
Adding bibliographical material on shelf was not successful.
Material is already on the shelf.
Permalink
URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year
Impact factor
Edition
Category
Classification
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Select the library membership card:
DRS,
in which the journal is indexed
Database name
Field
Year
Links to authors' personal bibliographies
Links to information on researchers in the SICRIS system
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
