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Recent advances in protection against doxorubicin-induced toxicityInjac, Rade ; Štrukelj, BorutAnthracycline antibiotics are among the most effective and commonly used anticancer drugs. Unfortunately, their clinical use is restricted by dose-dependent toxicity. Doxorubicin is an anthracycline ... antibiotic and cytotoxic (antineoplastic) agent. It is commonly used against ovarian, breast,lung, uterine and cervical cancers, Hodgkinćs disease, soft tissue and primary bone sarcomas, as well against in several other cancer types. It has been shown that free radicals are involved in doxorubicin-induced toxicity. Doxorubicin causes the generation of free radicals and the induction of oxidative stress, associated with cellular injury. This review illustrates recent applications of different natural products, drugs, drug delivery systems, and approaches for protection against doxorubicin-induced toxicity (2006-present).Source: Technology in cancer research and treatment. - ISSN 1533-0346 (Vol. 7, no. 6, 2008, str. 497-516)Type of material - article, component partPublish date - 2008Language - englishCOBISS.SI-ID - 2442097
Author
Injac, Rade |
Štrukelj, Borut
Topics
doksorubicin |
oksidativni stres |
toksikologija |
nanonkologija
source: Technology in cancer research and treatment. - ISSN 1533-0346 (Vol. 7, no. 6, 2008, str. 497-516)
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Database name | Field | Year |
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Injac, Rade | 30616 |
Štrukelj, Borut | 07849 |
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