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Identification of chromosomal regions associated with growth and carcass traits in an F3 full sib intercross line originating from a cross of chicken lines divergently selected on body weightTerčič, Dušan ...An F3 resource population originating from a croos between two divergently selected lines for high (D+line) or low (D-line) body at 8-weeks of age (BW55) was generated and used for Quantitative Trait ... Locus (QTL) mapping. From an initial cross of two founderF0 animals from D(+) and D(-) lines, progeny were randomly intercrossed over two generations following a full sib intercross line (FSIL) design. One hundred and seventy-five genome-wide polymorphic markers were employed in the DNA pooling and selective genotyping of F3 to identify markers with significant effects on BW55. Fifty-three markers on GGA2, 5 and 11 were then genotyped in the whole F3 population of 503 birds, where interval mapping with GridQTL software was employed. Eighteen QTL for body weight, carcass traits and some internal organ weights were identified. On GGA2, a comparison between 2-QTL vs. 1-QTL analysis revealed two separate QTL regions for body, feet, breast muscle and carcass weight. Given co-localization of QTL for some highly correlated traits, we concluded that there were 11 distinct QTL mapped. Four QTL localized to already mapped QTL from other studies, but seven QTL have not been previously reported and are hence novel and unique to our selection line. This study provides a low resolution QTL map for various traits and establishes a genetic resource for future fine-mapping and positional cloning in the advanced FSIL generations.Source: Animal genetics. - ISSN 0268-9146 (Vol. 40, no. 5, 2009, str. 743-748)Type of material - article, component partPublish date - 2009Language - englishCOBISS.SI-ID - 2452616
Author
Terčič, Dušan |
Holcman, Antonija |
Dovč, Peter, 1958- |
Morrice, D.R. |
Burt, David, Roslin Institute, UK |
Hocking, Paul M. |
Horvat, Simon
Topics
perutnina |
pitovni piščanci |
rast |
klavne lastnosti |
selekcija |
molekularna genetika |
QTL
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Terčič, Dušan | 14933 |
Holcman, Antonija | 08187 |
Dovč, Peter, 1958- | 05098 |
Morrice, D.R. | |
Burt, David, Roslin Institute, UK | |
Hocking, Paul M. | |
Horvat, Simon | 10412 |
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