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Prosti radikali in vloga antioksidantov v bioloških sistemih
Korošec, Ladko, 1946-2009
V telesu so prosti radikali v stalnem ravnoteÍju z antioksidanti. Kadar se ravnoteÍje poruǴi, kar imenujemo oksidativni stres, pride do poǴkodb celiřnihstruktur, ki so najpogostejǴi vzrok za ...staranje, degenerativne bolezni, raka, in razliřne bolezni. S poznavanjem vloge antioksidantov lahko uspeǴneje prepreřujemo in zdravimo te posledice. Pomembno je delovanje antioksidantov na protirakav tumorski supresijski gen p53, ki je regulator celiřnega ciklusa in proaptotiřni agens. Na tem naj bi temeljilo tudi protirakavo delovanje antioksidantov. Za racionalno in nenevarno uporabo antioksidantov je potrebno Ǵe boljǴe poznavanje patoloǴkih procesov in veriÍnih reakcij, ki jih povzrořajo prosti radikali.
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