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Disturbed estrogen and progesterone action in ovarian endometriosisŠmuc, Tina, 1980- ...Endometriosis is a very common disease in pre-menopausal women, where defective metabolism of steroid hormones plays an important role in its development and promotion. In the present study,we have ... examined the expression of 11 estrogen and progesterone metabolizing enzymes and their corresponding receptors in samples of ovarian endometriomas and control endometrium. Expression analysis revealed significant up-regulation of enzymesinvolved in estradiol formation (aromatase, sulfatase and all reductive17alpha-hydroxysteroid dehydrogenases) and in progesterone inactivation (AKR1C1 and AKR1C3).Among the estrogen and progesterone was up-regulated, and therewas no signreceptors, ERalpha was down-regulated, ERSource: Pre-receptor steroid metabolism as target for pharmacological treatment : May 26-28, 2008, Grainau, Germany (issues 1/2, Vol. 301, 2009, str. 59-64)Type of material - conference contributionPublish date - 2009Language - englishCOBISS.SI-ID - 24638937
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source: Pre-receptor steroid metabolism as target for pharmacological treatment : May 26-28, 2008, Grainau, Germany (issues 1/2, Vol. 301, 2009, str. 59-64)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Šmuc, Tina, 1980- | 25593 |
Hevir-Kene, Neli | 29240 |
Ribič-Pucelj, Martina | 05274 |
Husen, Bettina | ![]() |
Thole, Hubert | ![]() |
Lanišnik-Rižner, Tea | 11699 |
Source: Personal bibliographies
and: SICRIS
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