-
'Bad guys' among the antiparkinsonian drugsPirtošek, Zvezdan, 1956-The first effective drugs for Parkinson's disease (PD) were anticholinergics, introduced at the end of 19.th century by Charcot. Since the introduction of levodopa in the sixties of the previous ... century, many new drugs have emerged for the treatment of Parkinson's disease: dopamine agonists (ergot as well asnon-ergot, bromocriptine, pergolide, mirapexine, ropinirole), MAO B inhibitors (selegiline, rasagiline), amantadine, COMT inhibitors (entacapone, tolcapone). In all stages of the disease, levodopa remains the most effective drug for improving motor symptoms in PD. However, long term treatment with levodopa is accompanied by the development of motor fluctuations, dyskinesia, cognitive and neuropsychiatric adverse effects and increasingly diverse spectrum of drugs is needed to alleviate motor and nonmotor symptoms. Some of these drugs have caused considerable concern and controversies and were regarded at certain points as the 'bad guys' of Parkinson's disease pharmacological armamentarium. In the article, a short review of 'bad guys' including anticholinergics, selegiline, tolcapone and dopamine agonists, is given.Source: 1st Croatian Congress on Side Effects of Psychotropics with international participants : Some Selected Papers and Abstracts, February 26th - March 1st 2009, Osijek, Croatia (str. 114-118)Type of material - conference contributionPublish date - 2009Language - englishCOBISS.SI-ID - 26254553
Author
Pirtošek, Zvezdan, 1956-
Topics
Antiparkinson Agents |
Adverse Effects |
Therapeutic Use |
Benzophenones |
Adverse Effects |
Therapeutic Use |
Cholinergic Antagonists |
Adverse Effects |
Therapeutic Use |
Cognition |
Drug Effects |
Dopamine Agonists |
Adverse Effects |
Therapeutic Use |
Levodopa |
Adverse Effects |
Therapeutic Use |
Nitrophenols |
Adverse Effects |
Therapeutic Use |
Parkinson Disease |
Drug Therapy |
Mortality |
Selegiline |
Therapeutic Use |
Adverse Effects |
Survival Rate |
Treatment Outcome |
Dopaminski agonisti |
Parkinsonova bolezen |
Benzofenoni |
Spoznava |
Levodopa |
Selegilin |
Preživetje, stopnja |
Zdravljenje, izid |
Antiparkinsoniki |
Holinergični antagonisti |
Nitrofenoli
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Pirtošek, Zvezdan, 1956- | 05380 |
Select pickup location:
Material pickup by post
Notification
Subject headings in COBISS General List of Subject Headings
Select pickup location
Pickup location | Material status | Reservation |
---|
Please wait a moment.