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Alteration of skin laser-Doppler flux response to local cooling in gestational hypertensionCankar, Ksenija, 1965- ; Potočnik, Nejka ; Štrucl, MartinPurpose The pathophysiology of the pregnancy-induced hypertension is still poorly understood, especially with regard to the central autonomic nervous system control and peripheral vascular factors. ... Methods: Our study therefore aimed to investigate simultaneously the responses of blood pressure, heart rate, heart rate variability (HRV), and laser-Doppler (LD) flux to local cooling in healthy non-pregnant women (N = 12), in pregnant women with normal pregnancy (N = 16) and in women with gestational hypertension (N = 10). Results: The direct and indirect LD flux responses to local cold exposure werediminished in normotensive pregnant females (Dunnett's test, p < 0.05) when compared to non-pregnant females with normal menstrual cycle, but not in females with pregnancy-induced hypertension. In addition, blood pressure increased and heart rate decreased during cold exposure only in normotensive pregnant females, but not in pregnant hypertensive females (paired t test, p < 0.05). Simultaneously calculated heart rate variability total power of HRV and LF power values typically increased during local cold provocation test in non-pregnant females and in normotensive pregnant females (paired t test, p <0.05). In hypertensive pregnant females HRV indices remained unchanged. Conclusion: Our results indicate that the cardiovascular reactivity adaptationseen in normal pregnancy is absent in gestational hypertension.Source: Clinical autonomic research. - ISSN 0959-9851 (Letn. 20, št. 3, 2010, str. 183-190)Type of material - article, component partPublish date - 2010Language - englishCOBISS.SI-ID - 26730457
Author
Cankar, Ksenija, 1965- |
Potočnik, Nejka |
Štrucl, Martin
Topics
Pregnancy Complications, Cardiovascular |
Hypertension |
Heart Rate |
Laser-Doppler Flowmetry |
Cold |
Electrocardiography |
Mraz |
Srčna frekvenca |
Nosečnost, komplikacije kardiovaskularne |
Hipertenzija |
Laser-dopplersko merjenje hitrosti pretoka |
Elektrokardiografija
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Database name | Field | Year |
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Cankar, Ksenija, 1965- | 15243 |
Potočnik, Nejka | 05201 |
Štrucl, Martin | 09557 |
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