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Gullain-Barre-Strohlov sindrom = Guillain-Barre-Strohl syndromeSavanović, Vlado ; Rakuša, MartinGuillain-Barre-Strohlov (GBS) sindrom je akutna vnetna demielinizacijska poliradikulonevropatija. Za sindrom sta značilni limfocitna in makrofagna infiltracija z destukcijo mielina. V prvi vrsti so ... prizadete spinalne korenine in proksimalni deli živcev. Incidenca je od 0,6 do 2,0 na 100.000 prebivalcev. Od enega do štirih tednov pred nastankom GBS preboli okrog 66 % bolnikov blag respiratorni ali gastrointestinalni infekt. Osnovni značilnosti bolezni nujni za diagnozo GBS sta napredujoča in največkrat simetrična pareza vsaj dveh okončin ter prizadetost proprioceptivnih refleksov. GBS se značilno prične na spodnjih in nato napreduje na zgornji okončini. Največkrat so pareze proksimalne, hitro napredujoče in dosežejo vrh v 1 do 4 tednih. Klinično začetni hiporefleksiji sledi popolna arefleksija na prizadetih okončinah. Za potrditev diagnoze je obvezna preiskava likvorja ter meritve prevajanja po perifernem živčevju. Približno 20 % bolnikov zaradi težav z dihanjem nadaljuje zdravljenje na oddelku za intenzivno interno medicino (OIIM). 15 % bolnikov ozdravi brez posledic, pri 66 % ostanejo manjši nevrološki izpadi, 5 do 10 % bolnikov pa je trajno prizadetih zaradi parez. Mortaliteta znaša 2 do 6 % na 100.000 prebivalcev. GBS zdravimo intravensko s prečiščenim imunoglobulinom (IVIG) ali s plazmaferezo.Type of material - conference contribution ; adult, seriousPublish date - 2007Language - slovenianCOBISS.SI-ID - 2761023
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Savanović, Vlado | 27699 |
Rakuša, Martin | 28075 |
Source: Personal bibliographies
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