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Reliability of measurement techniques for the hepato-splanchnic region in multiple-trauma patientsKljučevšek, Damjana ; Kompan, LidijaRelevant information on the adequacy of intestinal perfusion is needed. The objective of our study was to investigate the relationship between the difference in intramucosal and arterial CO2 pressure ... (pCO2 gap) and the outcome in multiply injured patients and relations between the pCO2 gap and intestinal permeability (IP). Methods Forty consecutive multiply injured patients, admitted to the intensive care unit (ICU) of the University Medical Centre Ljubljana, were studied prospectively. On days 2 and 4, IP was measuredusing the lactulose-mannitol (L/M) test. For 4 days, the pCO2 gap was measured using air tonometry. Multiple organ failure (MOF) scores were calculated daily. Results No significant differences in the MOF scores and length of ICU stay were found between the groups formed with respect to the presumably normal pCO2 gap value of 1.33 kPa. The baseline pCO2 gap differencein patients with abdominal injuries was significantly (p = 0.01) higher in comparison with those without abdominal injuries. There was no correlation between the pCO2 gap values and L/M index measured simultaneously and also between the baseline and average pCO2 gap and L/M index measured on days 2 and 4. We were unable to find any association between the MOF score andpCO2 gap. The MOF score, however, correlated significantly with the L/M value determined on day 4 (r = 0.85, p = 0.02). The average gastric retention volume was inversely correlated with the average pCO2 gap (r = -0.33, p = 0.04). Conclusions The pCO2 gap in trauma patients on intragastric enteral nutrition in the phase of present technical solutions has no prognostic value for the development of MOF, but IP correlated with it.Source: European journal of trauma and emergency surgery. - ISSN 1863-9933 (Vol. 37, št. 6, 2011, str. 577-581)Type of material - article, component partPublish date - 2011Language - englishCOBISS.SI-ID - 27616473
Author
Ključevšek, Damjana |
Kompan, Lidija
Topics
Multiple Trauma |
Multiple Organ Failure |
Carbon Dioxide |
Partial Pressure |
Intestinal Mucosa |
Intensive Care Units |
Lactulose |
Diagnostic Use |
Mannitol |
Diagnostic Use |
Splanchnic Circulation |
Parcialni pritisk |
Ogljikov dioksid |
Politravma |
Mnogoorganska odpoved |
Črevesna sluznica |
Laktuloza |
Intenzivna oskrba, enote |
Splanhnični obtok |
Manitol
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Database name | Field | Year |
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Ključevšek, Damjana | 28454 |
Kompan, Lidija | 12255 |
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