ALL libraries (COBIB.SI union bibliographic/catalogue database)
-
Early cardiotoxicity after adjuvant concomitant treatment with radiotherapy and trastuzumab in patients with breast cancerMarinko, Tanja, medicina ...Z raziskavo smo želeli preveriti ali je med bolnicami, ki so ob zdravljenju s trastuzumabom pooperativno obsevale levo (skupina 1) oziroma desno (skupina 2) dojko/prsno steno, po zaključenem ... zdravljenju pomembna razlika v zgodnjih kazalcih kardiotoksičnosti. To smo merili z iztisnim deležem levega prekata (LVEF) in N-končnim pro-B natriuretičnim peptidom [NT-proBNP]). Bolniki in metode. V raziskavo smo vključili 175 zaporednih bolnic s pozitivnim HER2 rakom dojke, ki so v okviru dopolnilnega zdravljenja med junijem 2005 in decembrom 2010 prejemale trastuzumab ter smo jim sočasno pooperativno obsevali dojko/prsno steno. Vsem bolnicam smo ob začetku dopolnilnega zdravljenja naredili izhodiščno preiskavo srca, bodisi ehokardiografijo ali radioizotopno ventrikulografijo (LVEF0) ter naredili kontrolne meritve po zaključenem zdravljenju (LVEF1), hkrati pa smo jim določili vrednosti NT-proBNP. Analizirali smo razliko med LVEF0 in LVEF1 (% LVEF = LVEF0 -LVEF1) ter ju primerjali med skupinama. Rezultati. V skupini 1 je sodelovalo 84, v skupini 2 pa 91 bolnic. Mediani čas sledenja bolnic je bil 57 (37%71) mesecev. V skupini 1 je bila srednja vrednost % LVEF (%) -1,786 %, v skupini 2 pa -2,607 % (p = 0,562; interval zaupanja [CI]: od -2,004 do 3,648). Srednja vrednost NT-proBNP je bila 111,0 ng/l v skupini 1 in 90,0 ng/l v skupini 2 (p = 0,545). Primerjava ehokardiografskih kazalcev je pokazala, da bolnice iz skupine 1 niso imele pomembno slabše sistolične in diastolične funkcije levega prekata kot bolnice iz skupine 2, imele pa so pomembno več perikardnih izlivov (9 [11 %]) kot bolnice v skupini 2 (1 [1 %]) (p = 0,007). Zaključki. Med opazovanima skupinama nismo našli značilnih razlik v zgodnjih kazalcih kardiotoksičnosti (LVEF, NTproBNP). Bolnice, pri katerih smo obsevali levo dojko/prsno steno, so imele značilno več perikardnih izlivov.Source: Radiology and oncology. - ISSN 1318-2099 (Vol. 52, no. 2, June 2018, str. 204-212, VI)Type of material - article, component partPublish date - 2018Language - englishCOBISS.SI-ID - 2861179
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Marinko, Tanja, medicina | 34225 |
Borštnar, Simona, 1967- | 16303 |
Blagus, Rok | 30722 |
Dolenc, Jure, 1980- | 50156 |
Bilban-Jakopin, Cvetka | 20658 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: