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A double-blind placebo-controlled cross-over study on the effects of botulinum toxin type A on upper limb disorders = Dvojno slepa kontrolirana navzkrižna študija učinkov botulina A na bolezni zgornjih udov
Janša, Jelka ...
Botulinum treatment has been proven to be a promising treatment for many dystonic and spastic disorders. Apart from correction of posture and pain relief, functional testing is an important part of ...pre - and post-treatment assessment. We report results and dilemmas of using two assessment scales in adouble-blind, placebocontrolled cross-over study on 10 patients with upper limb motor disorders. While the improvement on the Arm Function Test (AFT) after the Botulinum session was not statistically significantly higher than after placebo, the difference in favour of the treatment was much more evidenton the 0-5 self-assessment scale. We believe that AFT is not sufficiently sensitive or at least not superior to simpler global scales, and that measurement of focal disability does not entirely clarify functional changes after treatment with Botulinum Toxin.
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