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Pomen intravenskih imunoglobulinov pri zdravljenju krvnih bolezni odraslih = The importance of intravenous immunoglobulins in the treatment of adult hematological diseasesGlaser, MarjanaIntravenski imunoglobulini (IVIG) so pripravki, narejeni iz človeške plazme, ki vsebujejo poleg imunoglobulina G še širok spekter protiteles za Slovenijo endemičnih povzročiteljev kužnih bolezni ter ... druge snovi. Uporaba pripravkov IVIG omogoča vzpostavitev normalnih imunoregulacijskih mehanizmov v telesu. Je kot nadomestno zdravljenje pri primarni in sekundarni imunski pomanjkljivosti (pomanjkanje protiteles, nezmožnost tvorbe protiteles), kot profilaktično zdravljenje pri nekaterih okužbah (citomegalovirus, parvovirus B19) ter kot zdravljenje avtoimunih bolezni, kot je idiopatska trombocitopenična purpura. Zaključki. S farmakokinetsko raziskavo pri bolnikih s kronično limfocitno levkemijo in plazmocitomom so dokazali, da priprava IVIG ne vpliva na normalno naravno porazdelitev IgG in drugih protiteles v pripravku. Številni možni mehanizmi za prikaz delovanja IVIG do danes še niso povsem razumljivi. Druga protitelesa v IVIG so zelo verjetno vpletena v delovanje. Sorazmerno dober učinek IVIG pri krvnih boleznih je postal zanimiv tudi za preprečevanje in zdravljenje nevroloških ter mišično-živčnih bolezni.Source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 77, št. 6/7, jun.-jul. 2008, str. 447-451)Type of material - article, component part ; adult, seriousPublish date - 2008Language - slovenianCOBISS.SI-ID - 3014975
Author
Glaser, Marjana
Topics
Immunoglobulins, Intravenous |
Imunoglobulini, intravenski |
Agammaglobulinemia |
Agamaglobulinemija |
Lymphoproliferative Disorders |
Limfoproliferativne motnje |
Multiple Myeloma |
Multipli mielom |
Purpura, Thrombocytopenic, Idiopathic |
Purpura, trombocitopenična, idiopatska
source: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 77, št. 6/7, jun.-jul. 2008, str. 447-451)
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Database name | Field | Year |
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Glaser, Marjana | 15864 |
Source: Personal bibliographies
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