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Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compoundsMirković, Bojana ...A new trick for an old dog! Aberrant cathepsin B activity is associated with tumor progression, however, despite extensive research, there are no cathepsinB inhibitors in clinical use. Here, ... nitroxoline, an established antimicrobial agent, is identified as a potent, reversible inhibitor of cathepsin B, and is thus a potential drug candidate for the treatment of cancer and other diseases in which cathepsin B activity plays a role.Source: ChemMedChem : Chemistry Enabling Drug Discovery. - ISSN 1860-7179 (Vol. 6, iss. 8, 2011, str. 1351-1356)Type of material - article, component partPublish date - 2011Language - englishCOBISS.SI-ID - 3024241
source: ChemMedChem : Chemistry Enabling Drug Discovery. - ISSN 1860-7179 (Vol. 6, iss. 8, 2011, str. 1351-1356)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Mirković, Bojana | 29604 |
Renko, Miha, 1980- | 25629 |
Turk, Samo | 29773 |
Sosič, Izidor | 30816 |
Jevnikar, Zala | 26497 |
Obermajer, Nataša | 25494 |
Turk, Dušan, 1959- | 04988 |
Gobec, Stanislav, 1970- | 15284 |
Kos, Janko, 1959- | 04648 |
Source: Personal bibliographies
and: SICRIS
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