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A 1:1 cocrystal of fluconazole with salicylic acidKastelic, Jože, farmacevt ...The interaction of the antifungal pharmaceutical agent fluconazole with salicylic acid in acetonitrile solution yields the 1:1 cocrystal ... 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol-2-hydroxybenzo ic acid (1/1), C13H12F2N6O C7H6O3. The asymmetric unit consists of one molecule of fluconazole and one molecule of salicylic acid, both in their neutral forms. Both crystal agents form head-to-tail hydrogen-bonded dimers, which are further connected into hydrogen-bonded extended zigzag tapes propagating along the ac diagonal.Source: Acta crystallographica. C, Crystal structure communications. - ISSN 0108-2701 (Vol. 67, part 9, 2011, str. o370-o372)Type of material - article, component partPublish date - 2011Language - englishCOBISS.SI-ID - 3075953
source: Acta crystallographica. C, Crystal structure communications. - ISSN 0108-2701 (Vol. 67, part 9, 2011, str. o370-o372)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Kastelic, Jože, farmacevt | |
Lah, Nina | 18837 |
Kikelj, Danijel | 01463 |
Leban, Ivan, 1947- | 03374 |
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