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MicroRNAs and long non-coding RNAs : prospects in diagnostics and therapy of cancerHauptman, Nina ; Glavač, DamjanBackground. Non-coding RNAs (ncRNAs) are key regulatory molecules in cellular processes, and are potentialbiomarkers in many diseases. Currently, microRNAs and long non-coding RNAs are being pursued ... as diagnostic andprognostic biomarkers, and as therapeutic tools in cancer, since their expression profiling is able to distinguish differentcancer types and classify their sub-types.Conclusions. There are numerous studies confirming involvement of ncRNAs in cancer initiation, development andprogression, but have only been recently identified as new diagnostic and prognostic tools. This can be beneficialin future medical cancer treatment options, since ncRNAs are natural antisense interactors included in regulationof many genes connected to survival and proliferation. Research is directed in development of useful markers fordiagnosis and prognosis in cancer and in developing new RNA-based cancer therapies, of which some are alreadyin clinical trials.Source: Articles from 7th Conference of experimental and translational oncology, [April, 20-24, 2013, Portorož] (Vol. 47, no. 4, dec. 2013, str. 311-318, I)Type of material - conference contributionPublish date - 2013Language - englishCOBISS.SI-ID - 30890969
Author
Hauptman, Nina |
Glavač, Damjan
Topics
microRNAs |
long non-coding RNAs |
biomarker |
microRNAs |
dolge nekodirane RNA molekule |
biomarker
source: Articles from 7th Conference of experimental and translational oncology, [April, 20-24, 2013, Portorož] (Vol. 47, no. 4, dec. 2013, str. 311-318, I)
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Hauptman, Nina | 27704 |
Glavač, Damjan | 09275 |
Source: Personal bibliographies
and: SICRIS
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