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Metoda določanja intrinzične aktivnosti sinteznih zaviralcev receptorja DC-SIGN : SI 23914 A (30. 04. 2013)Švajger, Urban ; Anderluh, Marko ; Jeras, MatjažTekom intenzivnih študij, ki so pripeljale do predloženega izuma, so tukajšnji izumitelji ugotovili, da lahko sklepamo o potencialnem agonizmu/antagonizmu sinteznih zaviralcev DC SIGN oz. njihovi ... intrinzični aktivnosti z metodo, ki zagotavlja gojenje dendritičnih celic v prisotnosti ali odsotnosti sinteznih zaviralcev DC-SIGN ob hkratni aktivaciji celic z TLR agonisti oz brez njih. Predloženi izum torej po prvem vidiku predstavlja metodo za določitev intrinzične aktivnosti sinteznih zaviralcev DC-SIGN na podlagi modulacije citokinskega profila dendritičnih celic ob prisotnosti ali odsotnosti TLR agonistov. Predloženi izum zagotavlja tudi uporabo metode za določevanje intrinzične aktivnosti sinteznih zaviralcev DC-SIGN za načrtovanje in sintezo novih sinteznih zaviralcev DC SIGN. Istočasno predloženi izum zagotavlja uporabo omenjene metode za oceno terapevtskega potenciala sinteznih zaviralcev DC-SIGN kot protimikrobnih učinkovin.Type of material - patentPublication and manufacture - Ljubljana : Urad RS za intelektualno lastnino, 2013Language - slovenianCOBISS.SI-ID - 3212145
Author
Švajger, Urban |
Anderluh, Marko |
Jeras, Matjaž
Topics
DC-SIGN |
sintezni zaviralci
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Švajger, Urban | 26198 |
Anderluh, Marko | 21456 |
Jeras, Matjaž | 01302 |
Source: Personal bibliographies
and: SICRIS
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