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Erythropoietin and its angiogenic activity [Elektronski vir]Kimáková, Patrícia ...Erythropoietin (EPO) is the main hematopoietic hormone acting on progenitor red blood cells via stimulation of cell growth, differentiation, and anti-apoptosis. However, its receptor (EPOR) is also ... expressed in various non-hematopoietic tissues, including endothelium. EPO is a pleiotropic growth factor that exhibits growth stimulation and cell/tissue protection on numerous cells and tissues. In this article we review the angiogenesis potential of EPO on endothelial cells in heart, brain, and leg ischemia, as well as its role in retinopathy protection and tumor promotion. Furthermore, the effect of EPO on bone marrow and adipose tissue is also discussed.Source: International journal of molecular sciences [Elektronski vir]. - ISSN 1422-0067 (Vol. 18, iss. 7, Jul. 2017, str. 1-14)Type of material - e-article ; adult, seriousPublish date - 2017Language - englishCOBISS.SI-ID - 33325785
Author
Kimáková, Patrícia |
Solár, Peter |
Solárová, Zuzana |
Komel, Radovan |
Debeljak, Nataša
Topics
eritropoetin |
receptor eritropoetina |
rak |
erythropoietin |
erythropoietin receptor |
cancer
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Kimáková, Patrícia | |
Solár, Peter | |
Solárová, Zuzana | |
Komel, Radovan | 06135 |
Debeljak, Nataša | 18622 |
Source: Personal bibliographies
and: SICRIS
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