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Sodobni pogled na nastanek osteoporoze = Up-to-date insight on the development of osteoporosisMencej Bedrač, Simona ...Ključna problema pri osteoporozi sta njena razširjenost in pozna diagnostika. Predvidevajo, da se bo število obolelih do leta 2050 podvojilo. Novejša dognanja kažejo, da razvoj osteoporoze poteka ... preko motenj v dveh glavnih regulatornih sistemih. Prvi, ki ga imenujemo RANKL/RANK/OPG, je ključen za nadzor osteoklastogeneze, drugi pa je signalna pot Wnt, ki ima osrednjo vlogo v osteoblastogenezi. Obstajajo dokazi, da so v patogenezo osteoporoze vpleteni tudi oksidativni stres, imunski sistem, vnetni citokini in procesi adipogeneze. Na razvoj osteoporoze vplivajo številni okoljski in genetski dejavniki. Na večino od njih nimamo vpliva, lahko pa z uravnoteženo prehrano zzadostno količino kalcija in vitamina D, redno telesno aktivnostjo, zdravim načinom življenja brez kajenja in čezmernega pitja alkoholnih pijač, pomembno zmanjšamo pojav bolezni.Source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 63, št. 5/6, dec. 2012, str. 269-278)Type of material - article, component partPublish date - 2012Language - slovenianCOBISS.SI-ID - 3372401
Author
Mencej Bedrač, Simona |
Ostanek, Barbara, 1972- |
Mlakar, Vid |
Zupan, Janja, farmacevtka |
Kocjan, Tomaž, 1966- |
Preželj, Janez |
Marc, Janja
Topics
osteoporoza |
patologija |
mehanizmi
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source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 63, št. 5/6, dec. 2012, str. 269-278)
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DRS, in which the journal is indexed
Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Mencej Bedrač, Simona | 24475 |
Ostanek, Barbara, 1972- | 18154 |
Mlakar, Vid | 25809 |
Zupan, Janja, farmacevtka | 32306 |
Kocjan, Tomaž, 1966- | 15783 |
Preželj, Janez | 01989 |
Marc, Janja | 12189 |
Source: Personal bibliographies
and: SICRIS
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